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Papers of the Week

Papers: 8 Oct 2022 - 14 Oct 2022

Animal Studies

2022 Oct 13

J Neural Eng

Spinal stimulation for motor rehabilitation immediately modulates nociceptive transmission.


Bandres MF, Gomes JL, McPherson JG
J Neural Eng. 2022 Oct 13.
PMID: 36228593.


Spinal cord injury (SCI) often results in debilitating movement impairments and neuropathic pain. Electrical stimulation of spinal neurons holds considerable promise both for enhancing neural transmission in weakened motor pathways and for reducing neural transmission in overactive nociceptive pathways. However, spinal stimulation paradigms currently under development for individuals living with SCI continue overwhelmingly to be developed in the context of motor rehabilitation alone. The objective of this study is to test the hypothesis that motor-targeted spinal stimulation simultaneously modulates spinal nociceptive transmission.