Browse by Audience
Skip to content
Papers of the Week
Corticotropin-releasing factor is involved in acute stress-induced analgesia and antipruritus.
Authors
Abstract
Under the condition of stress, the hypothalamic-pituitary-adrenal axis (HPA axis) is activated and causes the secretion of corticotropin-releasing factor (CRF). Previous studies have demonstrated that CRF is involved in the regulation of pain and itch. Thus, it remains worthy to explore whether the desensitization of pain and itch under high-intensity acute stress (such as high fear and tension) is related to the sharp increase of CRF.