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Papers of the Week
Persistent brain damage in reversible cerebral vasoconstriction syndrome on Tc-ethyl cysteinate dimer single-photon emission computed tomography: A long-term observational study.
Abstract
Blood-brain barrier (BBB) breakdown is considered a key step in the pathophysiology of reversible cerebral vasoconstriction syndrome (RCVS); however, its temporal course remains unclear. Based on the characteristics and dynamics of Tc-ethyl cysteinate dimer (Tc-ECD) as a tracer, Tc-ECD single-photon emission computed tomography (SPECT) can detect not only hypoperfusion but also BBB breakdown and/or brain tissue damage. Therefore, this study aimed to investigate this course using Tc-ECD SPECT.