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Papers of the Week


Can J Pain



Opioid reduction and enhanced recovery in orthopaedic surgery (OREOS): A feasibility randomized controlled trial in knee replacement patients.


Pallapothu S, Madden K, Adili A, Krsmanovic A, Nowakowski M, Packham T, Shoaib S, Thabane L, Tarride J-E, Tushinski D, Shanthanna H
Can J Pain. 2022; 6(4):1-2.
PMID: 36213524.


Total knee arthroplasties are the second most common surgery in Canada. Most patients recover well, but 20% or more still suffer from persistent pain and opioid use. Though opioids are an important part of perioperative pain management, their potential for long-term adverse effects is well recognized. Limiting opioids may be insufficient to overcome the issue of opioid overuse. Pain and opioid use are highly linked, so an effective alternative needs to address both issues.