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Papers of the Week

2022 Oct 07

Curr Pain Headache Rep

Pathophysiology of Chronic Migraine: Insights from Recent Neuroimaging Research.


Lin Y-K, Tsai C-L, Lin G-Y, Chou C-H, Yang F-C
Curr Pain Headache Rep. 2022 Oct 07.
PMID: 36207509.


Chronic migraine (CM) is a highly disabling primary headache disorder with a substantial impact on patients' quality of life. Episodic migraine (EM) and CM are dynamic states; CM usually evolves from EM alongside increased headache frequency, comorbidities, and medication overuse, supporting the notion that migraine is a spectrum disorder. This narrative review aims to summarize neuroimaging studies to better understand the pathophysiology of CM.