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Papers of the Week

Papers: 1 Oct 2022 - 7 Oct 2022

Pharmacology/Drug Development

2022 Oct 06

Endocr Metab Immune Disord Drug Targets

Transcriptional profiling of TGF-β superfamily members in lumbar DRGs of rats following sciatic nerve axotomy and activin C inhibits neuropathic pain.


Zhang F-M, Wang B, Hu H, Li Q-Y, Chen H-H, Luo L-T, Jiang Z-J, Zeng M-X, Liu X-J
Endocr Metab Immune Disord Drug Targets. 2022 Oct 06.
PMID: 36201267.


Neuroinflammation and cytokines play critical roles in neuropathic pain and axon degeneration/regeneration. Cytokines of transforming growth factor-β superfamily have implications in pain and injured nerve repair processing. However, the transcriptional profiles of the transforming growth factor-β superfamily members in dorsal root ganglia under neuropathic pain and axon degeneration/regeneration conditions remain elusive.