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Papers of the Week
Transcriptional profiling of TGF-β superfamily members in lumbar DRGs of rats following sciatic nerve axotomy and activin C inhibits neuropathic pain.
Abstract
Neuroinflammation and cytokines play critical roles in neuropathic pain and axon degeneration/regeneration. Cytokines of transforming growth factor-β superfamily have implications in pain and injured nerve repair processing. However, the transcriptional profiles of the transforming growth factor-β superfamily members in dorsal root ganglia under neuropathic pain and axon degeneration/regeneration conditions remain elusive.