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Papers of the Week


Papers: 1 Oct 2022 - 7 Oct 2022


Animal Studies, Pharmacology/Drug Development


2022 Oct 05


Eur J Pain

Response Profile in a Rat Model of Exercise-Induced Hypoalgesia is Associated with Duloxetine, Pregabalin and Diclofenac effect on Constriction Induced Neuropathy.

Abstract

Exercise is a known trigger of the inhibitory pain modulation system and its analgesic effect is termed Exercise-Induced Hypoalgesia (EIH). Previous studies have demonstrated that rats with deficient analgesic response following exercise develop more significant hypersensitivity following nerve injury compared to rats with substantial analgesic response following exercise.