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Papers of the Week
Response Profile in a Rat Model of Exercise-Induced Hypoalgesia is Associated with Duloxetine, Pregabalin and Diclofenac effect on Constriction Induced Neuropathy.
Abstract
Exercise is a known trigger of the inhibitory pain modulation system and its analgesic effect is termed Exercise-Induced Hypoalgesia (EIH). Previous studies have demonstrated that rats with deficient analgesic response following exercise develop more significant hypersensitivity following nerve injury compared to rats with substantial analgesic response following exercise.