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Papers of the Week


2022 Sep 01


BMJ Open


12


9

Paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty: protocol for the randomised, placebo-controlled, parallel 4-group, blinded, multicentre RECIPE trial.

Authors

Steiness J, Hägi-Pedersen D, Lunn T H, Lindberg-Larsen M, Graungaard B K, Lundstrom L H, Lindholm P, Brorson S, Bieder M J, Beck T, Skettrup M, von Cappeln A G, Thybo K H, Gasbjerg K S, Overgaard S, Jakobsen J C, Mathiesen O
BMJ Open. 2022 Sep 01; 12(9):e058965.
PMID: 36190737.

Abstract

Multimodal analgesia with paracetamol, non-steroidal anti-inflammatory drug and glucocorticoid is recommended for hip arthroplasty, but with uncertain effects of the different combinations. We aim to investigate benefit and harm of different combinations of paracetamol, ibuprofen and dexamethasone following total hip arthroplasty.