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Papers of the Week

2022 Sep 01

BMJ Open



Paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty: protocol for the randomised, placebo-controlled, parallel 4-group, blinded, multicentre RECIPE trial.


Steiness J, Hägi-Pedersen D, Lunn T H, Lindberg-Larsen M, Graungaard B K, Lundstrom L H, Lindholm P, Brorson S, Bieder M J, Beck T, Skettrup M, von Cappeln A G, Thybo K H, Gasbjerg K S, Overgaard S, Jakobsen J C, Mathiesen O
BMJ Open. 2022 Sep 01; 12(9):e058965.
PMID: 36190737.


Multimodal analgesia with paracetamol, non-steroidal anti-inflammatory drug and glucocorticoid is recommended for hip arthroplasty, but with uncertain effects of the different combinations. We aim to investigate benefit and harm of different combinations of paracetamol, ibuprofen and dexamethasone following total hip arthroplasty.