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Papers of the Week

Papers: 1 Oct 2022 - 7 Oct 2022

Human Studies, Pharmacology/Drug Development

2022 Oct

Neurosurg Focus



Spinal cord stimulation for treatment of chronic neuropathic pain in adolescent patients: a single-institution series, systematic review, and individual participant data meta-analysis.


Bakr SM, Knight JA, Shlobin NA, Budnick H, Desai V, Hill H, Johnson SK, Williams AE, Tolley JA, Raskin JS
Neurosurg Focus. 2022 Oct; 53(4):E13.
PMID: 36183181.


Neuropathic pain is undertreated in children. Neurosurgical treatments of pediatric chronic pain are limited by the absence of both US Food and Drug Administration approval and pediatric-specific hardware, as well as weak referral patterns due to a lack of physician education. This study presents a single-institution retrospective case series of spinal cord stimulation (SCS) in children ≤ 19 years of age and a systematic review of SCS in children. The authors' findings may further validate the role of SCS as an effective treatment modality for varied neuropathic pain syndromes found in pediatric patients.