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Papers of the Week

2022 Sep

Oxf Med Case Reports



A rare presentation of scrub typhus: myocarditis, acute liver failure and leukemoid reaction.


Mondal M K, Ghosh J, Bhattacharya B, Chatterjee N, Ghosh S
Oxf Med Case Reports. 2022 Sep; 2022(9):omac092.
PMID: 36176945.


Scrub typhus is a mite borne zoonosis, caused by , a gram-negative intracellular organism. This infection usually presents in high prevalence in the rural areas of East Asia and Western pacific islands. It usually presents with fever, chill, myalgia, headache, skin rashes, having pathognomonic and skin lesion i.e. eschar in ~10% cases in Indian subcontinent. It can present with life-threatening complications on occasional. The simultaneous presentation of more than two complications is uncommon, rarely reported in literature. Here we report a case of 37-year-old woman with acute febrile illness, complicated with myocarditis, acute liver failure and leukemoid reaction. She was diagnosed promptly and successfully treated with doxycycline with full recovery of the complications.