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Papers of the Week

2022 Sep

J Int Med Res



Spinal anaesthesia with clonidine: pain relief and earlier mobilisation after open nephrectomy – a randomised clinical trial.


Thurm M, Hultin M, Johansson G, Kröger Dahlin B-I, Winsö O, Ljungberg B
J Int Med Res. 2022 Sep; 50(9):3000605221126883.
PMID: 36177827.


Early mobilisation and effective pain management after open nephrectomy for renal cell carcinoma often include epidural analgesia (EDA), requiring an infusion pump and a urinary catheter, thus impeding mobilisation. Spinal anaesthesia (SpA) may be an alternative. This randomised clinical trial evaluated whether SpA improves analgesia and facilitates mobilisation over EDA and which factors influence mobilisation and length of stay (LOS).