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Papers of the Week

Papers: 24 Sep 2022 - 30 Sep 2022

Pharmacology/Drug Development

2022 Sep 28

Expert Opin Biol Ther

Effect of biological DMARDs and JAK inhibitors in pain of chronic inflammatory arthritis.


Alciati A, Di Carlo M, Siragusano C, Palumbo A, Masala I F, Atzeni F
Expert Opin Biol Ther. 2022 Sep 28.
PMID: 36168970.


The advent of biological disease-modifying anti-rheumatic drugs (bDMARDs) and, more recently, of Janus kinase inhibitors (JAKi) has had a major impact on the long-term outcomes of chronic inflammatory arthritis (IA). However, the persistence of pain, even in patients with a complete pharmacological control of peripheral inflammation, represents an important clinical challenge in the treatment of IA.