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Papers of the Week

2022 Jun

J R Coll Physicians Edinb



Hypercalcaemia and acute kidney injury: A rare presentation of seminoma.


Paris E, Fugaccia C, Hendry D, Findlay M, White J
J R Coll Physicians Edinb. 2022 Jun; 52(2):138-141.
PMID: 36146991.


Hypercalcaemia is common in patients with malignancy, but is rare in seminoma with only eight cases reported in the literature. We present an unusual case of a 36-year-old man who presented with hypercalcaemia and stage 3 acute kidney injury. He presented initially with headache and malaise, and was found to have markedly deranged blood tests. He underwent a renal biopsy before imaging confirmed an unexpected large abdominal mass, which was confirmed histologically to be a seminoma. He was referred to a tertiary oncology centre, and underwent emergency chemotherapy and radical resection with no evidence of recurrence to this date and with return to normocalcaemia.