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Papers of the Week

Papers: 24 Sep 2022 - 30 Sep 2022

2022 Sep 26

Scand J Pain

The link between epigenetics, pain sensitivity and chronic pain.


Giordano R, Petersen K K-S, Arendt-Nielsen L
Scand J Pain. 2022 Sep 26.
PMID: 36149940.


Increasing evidence suggests an association between gene expression and clinical pain. Epigenetic modifications are the main modulators of gene expression or protein translation in response to environmental stimuli and pathophysiological conditions. Preclinical and clinical studies indicate that epigenetic modifications could also impact the development of pain, the transition from acute to chronic pain, and the maintenance hereof.