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Papers of the Week


2022 Sep 20


Transpl Immunol

Stem cells as an ideal carrier for gene therapy: A new approach to the treatment of hepatitis C virus.

Authors

Rafati A, Ghaleh H E G, Azarabadi A, Masoudi M R, Afrasiab E, Alvanegh A G
Transpl Immunol. 2022 Sep 20:101721.
PMID: 36150664.

Abstract

Various chemical drugs have been approved for the treatment of patients with hepatitis C, but most of these treatments are costly, and also have an inadequate response and many side effects. Also, there is no effective vaccine for hepatitis C due to its high genetic diversity. In recent decades, clinical trials have grown dramatically regarding the benefits of stem cell therapy as a modulator of immune system responses and anti-inflammatory drugs. The most promising point in stem cell therapy and similar therapies is that patients with chronic pain and severe injuries are offered drug-free treatment or surgery. In the present study, we examine the various dimensions of the use of stem cells with the approach of gene therapy carriers as a new treatment method in the treatment of Hepatitis C.