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Papers of the Week

Papers: 17 Sep 2022 - 23 Sep 2022


J Pain Res


Full Recovery after Multiple Treatments with Injectable Ice Slurry.


Moradi Tuchayi S, Wang Y, Pence IJ, Fast A, Stemmer-Rachamimov A, Evans CL, Anderson RR, Garibyan L
J Pain Res. 2022; 15:2905-2910.
PMID: 36132994.


Cryoneurolysis uses tissue cooling as an opioid-sparing, long-lasting treatment for peripheral nerve pain. A nerve-selective method for cryoneurolysis by local injection of ice-slurry was developed to allow cryoneurolysis to be performed with a standard needle and syringe, similar to peripheral nerve blocks. Since the treatment of patients with chronic pain may require repeated injections, we investigated the safety and tolerance of repeated treatments in a rat model.