I am a
Home I AM A Search Login

Papers of the Week

Papers: 17 Sep 2022 - 23 Sep 2022

2022 Sep 14

Drug Alcohol Depend


The association of chronic pain and opioid withdrawal in men and women with opioid use disorder.


Ware OD, Ellis JD, Dunn KE, Hobelmann GJ, Finan P, Huhn AS
Drug Alcohol Depend. 2022 Sep 14; 240:109631.
PMID: 36126611.


Approximately 2.7 million individuals in the United States had an opioid use disorder (OUD) in 2020. Chronic pain may exacerbate opioid withdrawal severity, yet most research on opioid withdrawal has not collected data on chronic pain status. Moreover, there is limited evidence that women tend to experience greater opioid withdrawal severity than men, but large, confirmatory studies on this topic have not been published. The goal of this study was to examine the roles of chronic pain and gender on opioid withdrawal severity using a large, multi-site database.