Papers of the Week

Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2 and has a clinical presentation ranging from an asymptomatic course to flu-like syndrome up to respiratory failure. Seasonal Influenza, due to the influenza viruses and very common in children, can cause symptoms similar to COVID-19. In order to identify clinical and laboratory characteristics that allow healthcare workers to differentiate COVID-19 from Influenza, we performed a systematic review of the existing literature on the pediatric age. Methods. The research was done via PubMed for articles published from March 2020 to October 2021, combining the MeSH words "COVID-19" and "Influenza" and "Children" and considering the suggestions of the PRISMA Group.