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Papers of the Week

2022 Jul

Indian J Anaesth



Reliability of analgesia nociception index (ANI) and surgical pleth index (SPI) during episodes of bleeding – A pilot study.


Muthukalai S, Bansal S, Chakrabarti D, Umamaheswara Rao GS
Indian J Anaesth. 2022 Jul; 66(7):505-510.
PMID: 36111088.


Analgesia Nociception Index (ANI) and Surgical Pleth Index (SPI) are measures of nociception-antinociception balance during general anaesthesia. The validity of these two monitors during autonomic changes brought about by intraoperative blood loss and noradrenaline infusion has not been studied earlier. The primary objective of the study was to determine the effect of bleeding on ANI and SPI. The secondary objective was to observe the effect of noradrenaline infusion on ANI and SPI and the correlation between ANI and SPI.