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Papers of the Week

2022 Sep 16


Headache persisting after aneurysmal subarachnoid hemorrhage: A narrative review of pathophysiology and therapeutic strategies.


Sorrentino ZA, Laurent D, Hernandez J, Davidson C, Small C, Dodd W, Lucke-Wold B
Headache. 2022 Sep 16.
PMID: 36112096.


This narrative review of the literature concerns persistent headache attributed to past non-traumatic subarachnoid hemorrhage (SAH), based off demographic and clinical features, what are pathophysiologic mechanisms by which these headaches occur, which medical and interventional treatments have the most evidence for pain alleviation, and what pre-clinical evidence is there for emerging treatments for these patients.