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Papers of the Week


Papers: 10 Sep 2022 - 16 Sep 2022


Pharmacology/Drug Development


2022 Sep 09


Medicine (Baltimore)


101


36

Relative safety and efficacy of topical and oral NSAIDs in the treatment of osteoarthritis: A systematic review and meta-analysis.

Authors

Wang Y, Fan M, Wang H, You Y, Wei C, Liu M, Luo A, Xu X, Duan X
Medicine (Baltimore). 2022 Sep 09; 101(36):e30354.
PMID: 36086745.

Abstract

Osteoarthritis (OA) often affects the hands, knees, and hip joints, causing considerable pain and disability, and often affecting the patient's quality of life. Non-steroidal anti-inflammatory drugs (NSAIDs) are common pain relievers often applied as first line therapies for OA. However, prolonged NSAIDs application can have unwanted side effects. Given this, this study was designed to systematically evaluate the efficacy and safety of topical and oral NSAIDs for the treatment of OA.