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Papers of the Week

2022 Sep 05

Behav Brain Res

Neuroprotective effect of Anethole against rotenone induced non-motor deficits and oxidative stress in rat model of Parkinson’s disease.


Vastegani S M, Khoshnam S E, Mansouri E, Hajipour S, Ghafouri S, Bakhtiari N, Sarkaki A, Farbood Y
Behav Brain Res. 2022 Sep 05:114100.
PMID: 36075399.


Non-motor symptoms (NMS) have high prevalence in patients with Parkinson's disease (PD). These symptoms are mainly the result of increased oxidative stress and neuronal damage. In this study we investigated the possible neuroprotective effects of anethole as a potent antioxidant on rotenone-induced behavioral deficits, hippocampal neuronal death, and oxidative stress profile in rats.