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Papers of the Week


2022 Aug 31


West Afr J Med


39


8

Neurobiological Underpinnings in Drug Addiction.

Authors

Nwonu CNS, Nwonu PC, Ude RA
West Afr J Med. 2022 Aug 31; 39(8):874-884.
PMID: 36063103.

Abstract

Drug addiction is a chronic biochemical drug use disorder that affects the human brain and behaviour, and leads to an uncontrollable use of a licit or illicit drug. Drug addiction can commence, usually in the young, with the use of a non-medical or a recreational drug in social gatherings, which becomes more frequent over a period of time. It is associated with incremental doses of the drug in order to achieve a state of euphoria. Addiction to drugs has been identified as a relevant social and health problem presenting a risk to public health, especially with regards to communicable diseases (e.g., HIV and AIDS, hepatitis B or C, tuberculosis, and sexually transmitted infections).