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Papers of the Week

2022 Sep 03

Anaesth Crit Care Pain Med

Plasmatic catecholamines after neuraxial labour analgesia: A randomised controlled trial comparing epidural versus combined spinal-epidural.


Santos S A, Fernandes H D S, Souza Nani F, Gonzaga Bartilotti A, Pulcineli Vieira Francisco R, Carmona M J C, Bliacheriene F, Vieira J E
Anaesth Crit Care Pain Med. 2022 Sep 03:101148.
PMID: 36067925.


Combined spinal-epidural technique (CSE) for labour analgesia has been associated with fetal bradycardia and uterine hypertonia when compared with epidural analgesia (EA), possibly due to a decrease in epinephrine levels following neuraxial anaesthesia. However, there are no recent studies comparing plasmatic catecholamines levels between those two techniques. This study aimed to compare CSE versus EA regarding pre- and post-analgesia catecholamines levels, uterine tone and fetal heart rate.