Browse by Audience
Skip to content
Papers of the Week
Thermal Antinociceptive Responses to Alcohol in DBA/2 J and C57BL/6 J Inbred Male and Female Mouse Strains.
Abstract
The phenomenon of alcohol analgesia and tolerance can facilitate misuse and lead to the development of alcohol use disorder (AUD). Numerous alcohol-induced behaviors are genetically influenced; however, it is unknown if alcohol analgesia has a genetic contribution. Rodent studies have shown that alcohol responses differ vastly between two widely studied inbred strains of mice, C57BL/6J (B6) and DBA/2J (D2). Here, we used B6 and D2 mice as an initial behavioral genetic analysis of acute alcohol-induced antinociception.