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Papers of the Week

2022 Aug 31

CNS Neurol Disord Drug Targets

Comparison of the sedative effect of ketamine, magnesium sulfate, and propofol in patients undergoing upper gastrointestinal endoscopy: Double-blinded randomized clinical trial.


Shafiee H, Riahipour F, Hormati A, Ahmadpour S, Habibi M A, Vahedian M, Aminnejad R, Saeidi M
CNS Neurol Disord Drug Targets. 2022 Aug 31.
PMID: 36045520.


Endoscopy provides valuable diagnostic informationand intervention therapies for gastroenterologists. Therefore, various drugs have been used to induce sedation in patients undergoing endoscopy, whereas none have been considered definitely preferred by endoscopists. In the current study, we decided to use the combination of magnesium sulfate, ketamine, and their synergistic effects for creating partial analgesia to increase the satisfaction of endoscopists and patients.