I am a
Home I AM A Search Login

Papers of the Week

2022 Jul 15

World J Gastrointest Oncol



Primary signet-ring cell carcinoma of the extrahepatic bile duct: A case report.


Xie C-B, Wu Y, Li F, Zhao K-F, Shi R-S, Huang Q, Ao J, Ke D
World J Gastrointest Oncol. 2022 Jul 15; 14(7):1356-1362.
PMID: 36051105.


Signet ring cell carcinoma (SRCC) is a specific type of mucinous secretory adenocarcinoma, which contains abundant mucus in the cytoplasm and pushes the nucleus to one side of the cell membrane, forming a round or oval, and the nuclear deviations give the cells a signet ring-like appearance. SRCC often originates in the gastrointestinal tract, especially in the stomach. However, primary SRCC of the extrahepatic bile duct is extremely rare. Therefore, little is known about its epidemiology, treatment, and prognosis.