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Papers of the Week


2022 Aug 27


Acta Anaesthesiol Scand

Markers of neutrophil mediated inflammation associate with disturbed continuous electroencephalogram after out of hospital cardiac arrest.

Authors

Pekkarinen PT, Carbone F, Minetti S, Ramoni D, Ristagno G, Latini R, Wihersaari L, Blennow K, Zetterberg H, Toppila J, Jakkula P, Reinikainen M, Montecucco F, Skrifvars MB
Acta Anaesthesiol Scand. 2022 Aug 27.
PMID: 36053856.

Abstract

Achieving an acceptable neurological outcome in cardiac arrest survivors remains challenging. Ischaemia-reperfusion injury induces inflammation, which may cause secondary neurological damage. We studied the association of ICU admission levels of inflammatory biomarkers with disturbed 48-hour continuous electroencephalogram (cEEG), and the association of the daily levels of these markers up to 72 hours with poor 6-month neurological outcome.