I am a
Home I AM A Search Login

Papers of the Week

Papers: 3 Sep 2022 - 9 Sep 2022

Animal Studies

2022 Sep 02

Arthritis Rheumatol

R399E, a mutated form of Growth and Differentiation Factor 5, for disease modification of osteoarthritis.


Gigout A, Werkmann D, Menges S, Brenneis C, Henson F, Cowan KJ, Musil D, Thudium CS, Gühring H, Michaelis M, Kleinschmidt-Doerr K
Arthritis Rheumatol. 2022 Sep 02.
PMID: 36054172.


To preclinically characterize a mutant form of growth and differentiation factor 5 (GDF5, R399E) with reduced osteogenic properties, as a potential disease-modifying osteoarthritis (OA) drug.