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Papers of the Week

Papers: 27 Aug 2022 - 2 Sep 2022

Pharmacology/Drug Development

2022 Aug 29

Curr Neurovasc Res

Caffeic Acid Phenethyl Ester (CAPE) Attenuates Paclitaxel-Induced Peripheral Neuropathy: A Mechanistic Study.


Kulkarni N P, Vaidya B, Narula AS, Sharma S S
Curr Neurovasc Res. 2022 Aug 29.
PMID: 36043777.


Chemotherapy-induced peripheral neuropathy is a debilitating pain syndrome produced as a side effect of antineoplastic drugs like paclitaxel. Despite efforts, the currently available therapeutics suffer from serious drawbacks like unwanted side effects, poor efficacy and provide only symptomatic relief. Hence, there is a need to find new therapeutic alternatives for the treatment of Chemotherapy-induced peripheral neuropathy.