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Papers of the Week
Caffeic Acid Phenethyl Ester (CAPE) Attenuates Paclitaxel-Induced Peripheral Neuropathy: A Mechanistic Study.
Abstract
Chemotherapy-induced peripheral neuropathy is a debilitating pain syndrome produced as a side effect of antineoplastic drugs like paclitaxel. Despite efforts, the currently available therapeutics suffer from serious drawbacks like unwanted side effects, poor efficacy and provide only symptomatic relief. Hence, there is a need to find new therapeutic alternatives for the treatment of Chemotherapy-induced peripheral neuropathy.