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Papers of the Week

2022 Jul




Evaluation of the Antinociceptive Action of Simvastatin in Mice.


Katole NT, Kale JS, Salankar HV
Cureus. 2022 Jul; 14(7):e26910.
PMID: 35983393.


Statins are well-established agents for dyslipidemia and have successfully been used for the prevention of coronary artery diseases for a long time; this is attributed not only to their lipid-lowering action but also to their pleiotropic actions. Recently many pleiotropic actions of statins have been explored, but very few studies were done to explore statins' antinociceptive action; therefore, the current study was planned to evaluate the antinociceptive activity of Simvastatin in different pain models in mice.