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Papers of the Week


2022 Aug 16


Lancet Microbe

Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis.

Authors

Jalalzadeh H, Groenen H, Buis DR, Dreissen Y E, Goosen J H, Ijpma F F, van der Laan MJ, Schaad RR, Segers P, van der Zwet WC, Griekspoor M, Harmsen WJ, Wolfhagen N, Boermeester MA
Lancet Microbe. 2022 Aug 16.
PMID: 35985350.

Abstract

Surgical site infection (SSI) is the most common postoperative complication and substantially increases health-care costs. Published meta-analyses and international guidelines differ with regard to which preoperative skin antiseptic solution and concentration has the highest efficacy. We aimed to compare the efficacy of different skin preparation solutions and concentrations for the prevention of SSIs, and to provide an overview of current guidelines.