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Papers of the Week

2022 Aug 16

Inflamm Bowel Dis

Patient-Reported Outcomes Correlate With Microbial Community Composition Independent of Mucosal Inflammation in Pediatric Inflammatory Bowel Disease.


Hellmann J, Ta A, Ollberding NJ, Bezold R, Lake K, Jackson K, Dirksing K, Bonkowski E, Haslam DB, Denson LA
Inflamm Bowel Dis. 2022 Aug 16.
PMID: 35972440.


Inflammatory bowel diseases (IBDs) involve an aberrant host response to intestinal microbiota causing mucosal inflammation and gastrointestinal symptoms. Patient-reported outcomes (PROs) are increasingly important in clinical care and research. Our aim was to examine associations between PROs and fecal microbiota in patients 0 to 22 years of age with IBD.