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Papers of the Week

2022 Jul 28



A discovery of clinically approved Panlongqi Tablet for repositioning to treat osteoarthritis by inhibiting PI3K/AKT activation.


Wang L, Xu P, Xu Y, Cui R, Yang Y, Zou Z, Du H, Zhu C, Zhang G, Han T, Lin N
Phytomedicine. 2022 Jul 28; 105:154360.
PMID: 35964457.


Panlongqi Tablet (PLQT) is a Chinese patent drug composed of 29 kinds of traditional Chinese medicines. Clinical practice has shown that PLQT can relieve osteoarthritis-caused joint pain, but its effects and mechanisms in other pathological links of osteoarthritis have not been characterized.