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Papers of the Week


2022 Jul 28


Phytomedicine


105

A discovery of clinically approved Panlongqi Tablet for repositioning to treat osteoarthritis by inhibiting PI3K/AKT activation.

Authors

Wang L, Xu P, Xu Y, Cui R, Yang Y, Zou Z, Du H, Zhu C, Zhang G, Han T, Lin N
Phytomedicine. 2022 Jul 28; 105:154360.
PMID: 35964457.

Abstract

Panlongqi Tablet (PLQT) is a Chinese patent drug composed of 29 kinds of traditional Chinese medicines. Clinical practice has shown that PLQT can relieve osteoarthritis-caused joint pain, but its effects and mechanisms in other pathological links of osteoarthritis have not been characterized.