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Papers of the Week


Papers: 13 Aug 2022 - 19 Aug 2022


Human Studies

PAIN TYPE:
Migraine/Headache


2022 Aug 11


Neuromodulation

Long-Term Prophylactic Transcranial Direct Current Stimulation Ameliorates Allodynia and Improves Clinical Outcomes in Individuals With Migraine.

Authors

Aksu S, Cerrahoğlu Şirin T, Hasırcı Bayır B R, Ulukan Çağrı, Soyata A Z, Kurt A, Karamürsel S, Baykan B
Neuromodulation. 2022 Aug 11.
PMID: 35965182.

Abstract

Migraine is a common and substantially debilitating disorder that may associate with allodynia, a marker of central sensitization in the pain circuits. Several unmet needs, like limited adherence to drugs due to adverse events and cost-effectivity, still occur in the prophylactic treatment of migraine. Transcranial direct current stimulation (tDCS) has recently been indicated to be beneficial in individuals with migraine with and without allodynia. However, to our knowledge, there are no studies evaluating the efficacy of six-month tDCS in migraine.