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Papers of the Week

2022 Aug 11

Ann R Coll Surg Engl

Penthrox enables quicker management of fractures, dislocations and more: learning lessons from expedited care of trauma patients during the COVID-19 pandemic.


Gray Stephens C, Dias A, Skinner E, Brennan C, Middleton RG, Angel CK
Ann R Coll Surg Engl. 2022 Aug 11.
PMID: 35950512.


Methoxyflurane is an historical anaesthetic agent that has undergone a renaissance with the introduction of a smaller dose in a handheld 'Penthrox' device. The benefits of Penthrox include its ease of use, with disposable individual packets, and the need for less monitoring and staff, when compared with deeper sedation. The literature acknowledges its use for analgesia and in the management of anterior shoulder dislocation but in no other procedural orthopaedic circumstance.