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Papers of the Week

Papers: 6 Aug 2022 - 12 Aug 2022


2022 Aug 11

J Headache Pain



Avoid or seek light – a randomized crossover fMRI study investigating opposing treatment strategies for photophobia in migraine.


Matt E, Aslan T, Amini A, Sariçiçek K, Seidel S, Martin P, Wöber C, Beisteiner R
J Headache Pain. 2022 Aug 11; 23(1):99.
PMID: 35948966.


Photophobia, the aberrantly increased sensitivity to light, is a common symptom in migraine patients and light discomfort is frequently found as a trigger for migraine attacks. In behavioral studies, planned exposure to light was found to reduce headache in migraine patients with photophobia, potentially by increasing habituation to this migraine trigger. Here, we aimed to elucidate neurophysiological mechanisms of light exposure versus light deprivation in migraine patients using functional magnetic resonance imaging (fMRI).