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2022 Aug 04
Clin Gastroenterol Hepatol
Primary sclerosing cholangitis (PSC) is a major unmet medical need in clinical hepatology. Cilofexor is a non-steroidal FXR agonist being evaluated for the treatment of PSC. Here, we describe the safety and preliminary efficacy of cilofexor in a 96-week, open-label extension (OLE) of a phase 2 trial.