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gy2022-1-3
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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Long Non-Coding RNA and mRNA Profiles in the Spinal Cord of Rats with Resiniferatoxin-Induced Neuropathic Pain.

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Papers: 6 Aug 2022 - 12 Aug 2022


Animal Studies


2022


J Pain Res


http://www.ncbi.nlm.nih.gov/pubmed/35935680?dopt=Abstract


15

Long Non-Coding RNA and mRNA Profiles in the Spinal Cord of Rats with Resiniferatoxin-Induced Neuropathic Pain.

Authors

Long Non-Coding RNA and mRNA Profiles in the Spinal Cord of Rats with Resiniferatoxin-Induced Neuropathic Pain.
Wu C, Liu Y, Wan K, Lan Y, Jia M, Lin L, Gao S, Chen K, Yang J, Pan H-L, Li M, Mao H
J Pain Res. 2022; 15:2149-2160.
PMID: 35935680.

Abstract

The ultrapotent transient receptor potential vanilloid 1 (TRPV1) agonist resiniferatoxin (RTX) induces small-fiber sensory neuropathy, which has been widely used model of postherpetic neuralgia to study mechanisms of neuropathic pain and new analgesics. The long non-coding RNA (lncRNA) and mRNA expression profiles in spinal dorsal horn tissues of rats six weeks after RTX injection to identify new RNAs related to neuropathic pain.
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