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Papers of the Week

2022 Aug

Clin Case Rep



Herpes simplex virus infection: Management of primary oral lesions in children.


Khalifa C, Slim A, Maroua G, Sioud S, Hentati H, Selmi J
Clin Case Rep. 2022 Aug; 10(8).
PMID: 35937022.


Primary herpetic gingivostomatitis (PHGS) represents the most observed clinical feature of primary herpes infection with the simplex virus (HSV). It is often caused by HSV-1 and affects children most of the time. Unlike, the majority of primary HSV infections that is asymptomatic. It may be preceded by some prodromal symptoms like fever, anorexia, irritability, malaise, and headache. After the resolution of the primary infection, the virus remains latent in a nervous ganglion. The aim of the present paper was to report a case of severe PHGS with herpetic whitlow in a 10-year-old child.