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Papers of the Week


2022 Aug 05


Histol Histopathol

Nerve changes associated with post thoracotomy pain syndrome.

Authors

Petrache I-A, Sharma A, Kumar A, Baderca F, Neagoe O C, Tudorache E, Oancea C, Jifcu M E, Ionica M, Kundnani N R, Gabriel C, Burlacu O
Histol Histopathol. 2022 Aug 05:18515.
PMID: 35929136.

Abstract

Chronic post-thoracotomy pain (PTPS) is a frequent complication of thoracic operations. Sometimes the pain is excruciating enough to impair activities of daily living (ADL). All thoracic procedures have the potential to cause trauma to the intercostal nerves due to retractor use, chest closure techniques, and or wound healing. In our study, we analyzed the microscopic aspects of the nerves involved in the healing process, to better understand the histopathology of chronic pain.