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Papers of the Week


2022 Jul 30


Dermatol Ther (Heidelb)

Randomized Clinical Trial of Conventional versus Indoor Daylight Photodynamic Therapy for Treatment of Actinic Cheilitis.

Authors

Arisi M, Galli B, Pisani E G, La Rosa G, Licata G, Rovaris S, Tomasi C, Rossi M T, Venturini M, Spiazzi L, Calzavara-Pinton P
Dermatol Ther (Heidelb). 2022 Jul 30.
PMID: 35907163.

Abstract

Actinic cheilitis (AC) is the biologic precursor of invasive squamous cell carcinoma (SCC) of the vermilion, and different treatment options have been investigated, but their efficacy is hampered by local inflammation, pain and slow recovery. Daylight photodynamic therapy (dl-PDT) has been demonstrated to represent a valuable treatment option for AC, but its feasibility is limited by weather conditions and latitude.