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Papers of the Week


2022 Jul 27


Trials


23


1

Ketamine for acute pain after trauma: the KAPT randomized controlled trial.

Authors

Puzio TJ, Klugh J, Wandling MW, Green C, Balogh J, Prater SJ, Stephens CT, Sergot PB, Wade CE, Kao LS, Harvin JA
Trials. 2022 Jul 27; 23(1):599.
PMID: 35897081.

Abstract

Evidence for effective pain management and opioid minimization of intravenous ketamine in elective surgery has been extrapolated to acutely injured patients, despite limited supporting evidence in this population. This trial seeks to determine the effectiveness of the addition of sub-dissociative ketamine to a pill-based, opioid-minimizing multi-modal pain regimen (MMPR) for post traumatic pain.