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Papers of the Week


2022 Jul 01


J Neurosurg Pediatr

The usefulness and safety of dexmedetomidine for postoperative sedation in pediatric patients with moyamoya disease.

Authors

Kanamori F, Araki Y, Yokoyama K, Uda K, Kurimoto M, Shiba Y, Mamiya T, Takayanagi K, Ishii K, Nishihori M, Izumi T, Okamoto S, Saito R
J Neurosurg Pediatr. 2022 Jul 01:1-7.
PMID: 35901711.

Abstract

After revascularization surgery in pediatric patients with moyamoya disease (MMD), resting and avoiding crying is important. However, this inaction is often difficult because of pain or anxiety. Dexmedetomidine (DEX), which has sedative and analgesic properties, may be useful in reducing those uncomfortable conditions; however, its common side effects include bradycardia and hypotension, which have a risk of decreasing the cerebral blood flow. The aim of this study was to investigate the efficacy and safety of using DEX for pediatric patients with MMD in the acute period after revascularization surgery.