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Papers of the Week


2022


Int J Gen Med


15

A Pilot Mitochondrial Genome-Wide Association on Migraine Among Saudi Arabians.

Authors

Al Asoom L, Khan J, Sunni A A, Rafique N, Latif R, Alabdali M, Abdulazeez S, Borgio FJ
Int J Gen Med. 2022; 15:6249-6258.
PMID: 35903646.

Abstract

Mitochondrial DNA (mtDNA) mutations have been reported in multiple neurological diseases and helped to explain the pathophysiology of these diseases. Similarly, variations in mtDNA might exist in migraine and can explain the effect of low ATP production in the neurons on the initiation of migraine attack. Therefore, in the current study we aim to explore the association of mtDNA mutations on migraine in the Saudi population.