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Papers of the Week

2022 Jul 19

Rev Esp Anestesiol Reanim (Engl Ed)

Opioid-free anesthesia for open radical cystectomy in morbid obesity.


Malo-Manso A, Ramírez-Aliaga M, Sepúlveda-Haro E, Díaz-Crespo J, Escalona-Belmonte JJ, Guerrero-Orriach JL
Rev Esp Anestesiol Reanim (Engl Ed). 2022 Jul 19.
PMID: 35869004.


Opioid-free anaesthesia shows evidence about its efectivity and security, even though its risks and benefits are not well defined. Neither are the patient profile or sort of surgery where it could be superior to the conventional opioid-based anaesthetic technique. Aggressive and/or long-lasting surgeries set out several queries on this technique regarding sudden hemodynamic changes, as it does not produce sympatholysis through μ receptor and there is modest experience in this technique. A morbidly obese patient received open radical cystectomy with Bricker-type urinary diversion using infraumbilical incision under OFA protocol, maintaining an adequate hemodynamic stability and excellent analgesia in postoperatory care without using any intraoperative opioids. Opioid-free anaesthesia technique is developing its evidence. However, it is necessary to keep on researching its clinical applications, different drug combinations and solutions to its expected complications.