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Papers of the Week


2022 Jul 22


BMC Musculoskelet Disord


23


1

Apparent diffusion coefficient values in Modic changes – interobserver reproducibility and relation to Modic type.

Authors

Dagestad MH, Vetti N, Kristoffersen PM, Zwart J-A, Storheim K, Bakland G, Brox JI, Grøvle L, Marchand GH, Andersen E, Assmus J, Espeland A
BMC Musculoskelet Disord. 2022 Jul 22; 23(1):695.
PMID: 35869480.

Abstract

Modic Changes (MCs) in the vertebral bone marrow were related to back pain in some studies but have uncertain clinical relevance. Diffusion weighted MRI with apparent diffusion coefficient (ADC)-measurements can add information on bone marrow lesions. However, few have studied ADC measurements in MCs. Further studies require reproducible and valid measurements. We expect valid ADC values to be higher in MC type 1 (oedema type) vs type 3 (sclerotic type) vs type 2 (fatty type). Accordingly, the purpose of this study was to evaluate ADC values in MCs for interobserver reproducibility and relation to MC type.