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Papers of the Week


2022 Jul 19


Brain Res Bull

Dual orexin receptor antagonist drug suvorexant can help in amelioration of predictable chronic mild stress-induced hyperalgesia.

Authors

Chavan P, Chikahisa S, Shiuchi T, Shimizu N, Dalanon J, Okura K, Séi H, Matsuka Y
Brain Res Bull. 2022 Jul 19.
PMID: 35868501.

Abstract

This study aimed to evaluate the involvement of the orexin system in predictable chronic mild stress (PCMS) and the effects of suvorexant, a dual orexin receptor antagonist, on nociceptive behavior in PCMS.