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Papers of the Week


2022 Jul 19


J Ethnopharmacol

The antinociceptive and anti-inflammatory potential and pharmacokinetic study of significant alkamides ingredients from Asarum Linn.

Authors

Liu H, Li S, Huan X, Xie Y, Xie Z, Sun Y, Cao N, Xie Q, Wang Y, Wang H, Cheng X, Guan H, Wang C
J Ethnopharmacol. 2022 Jul 19:115569.
PMID: 35868550.

Abstract

Asari Radix et Rhizoma (ARR), including 3 major plants of genus Asarum Linn, A. heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag., A. sieboldii Miq. f. sieboldii and A. sieboldii Miq f. seoulense (Nakai) C. Y. Cheng et C. S. Yang, is one of the most important traditional herbal medicine in Asia with tremendous pharmacological activities. For a long time, researchers focus attention on studing asarinin and essential oils, the indicating ingredients of ARR, but paid less attention to another characteristic component, alkamides. The role of alkamides in the major efficacy of ARR medication remains to be elucidated.